Skin whitening tests (Long-term tests in humans)


Characteristics

A variety of in vitro tests are conducted to evaluate the efficacy of skin whiteners, but ultimately tests are must be conducted on actual biological skin. At Nikoderm Research, we advocate an evaluation system able to handle the entire process from data for promotional material to submission of applications for quasi-drugs.

 

Test outline

The pigmentation inhibitory action achieved through application of the test sample is evaluated in volunteers with pigmentation (spots) and on pigmentation artificially created with UV light.

 

 

Test examples

■ Evaluation of inhibitory effect on artificially created pigmentation

 

 A pigmentation site is created artificially using a solar simulator and improvements in pigmentation with long-term use of the test sample is evaluated. Evaluation methods include measuring skin color and visual judgments by experienced evaluators or dermatologists.

 

■ Evaluation of pigmentation inhibitory effect in volunteers with spots

 

 

Volunteers with spots use the test sample long term and the pigmentation inhibitory effect of the test sample is evaluated by measuring skin color and with visual judgments by experienced evaluators or dermatologists.