Company Infomation

Nikoderm Research Inc.

Address 1-6-14 Azuchimachi,Chuo-ku, Osaka City, OSAKA 541-0052, JAPAN
TEL  +81-6-6125-3501
FAX   +81-6-6125-3530
President Shoichi Yahagi


-Safety/efficacy evaluation of cosmetics/pharmaceutical raw materials and preparations

-Proposal of appropriate evaluation methods


Main Service

Safety evaluation

Human object test

Primary skin irritation

Skin sensitization

Stinging test

Efficacy evaluation In vitro test

Cell activations

Cell proliferation

Oxidative stress resistance

Collagen synthesis

Hyaluronic acid synthesisi

MMP-1 synthesis

Elastase activity

Tyrosinase activity


Tyrosinase synthesis

In vivo test

Physiological effects on the skin

Skin lightening


Hair growing

Effects of long-term application of cosmetics

SPF/PA measurement

Sale of reconstructed 3-D models(SkinEthic Laboratories) in Japan  

Reconstructed human epidermal models(Episkin,RHE)

Reconstructed human pigmented model(RHPE)

Reconstructed human cornel epithelial model(HCE)


 *Nikoderm also performs safety and efficacy evaluations using the abovementioned models.


2003 Establishment of Nikoderm Research Inc.

2004 Installation of evaluation rooms and cell culture rooms in Head Office

2009 Conclusion of agreement with SkinEthic Laboratories,France,as its exclusive agent in Japan