NIKODERM RESEARCH INC.
| Address | 1-6-14 Azuchimachi,Chuo-ku, Osaka City, OSAKA 541-0052, JAPAN |
| TEL | +81-6-6125-3501 |
| FAX | +81-6-6125-3530 |
| [email protected] | |
| President | Shoichi Yahagi |
-Safety/efficacy evaluation of cosmetics/pharmaceutical raw materials and preparations
-Proposal of appropriate evaluation methods
|
Safety evaluation |
Human object test |
Primary skin irritation Skin sensitization Stinging test |
| Efficacy evaluation | In vitro test |
Cell activations Cell proliferation Oxidative stress resistance Collagen synthesis Hyaluronic acid synthesisi MMP-1 synthesis Elastase activity Tyrosinase activity Melanogenesis Tyrosinase synthesis |
| In vivo test |
Physiological effects on the skin Skin lightening Anti-wrinkle, Hair growing Effects of long-term application of cosmetics SPF/PA measurement |
|
| Sale of reconstructed 3-D models(SkinEthic Laboratories) in Japan |
Reconstructed human epidermal models(Episkin,RHE) Reconstructed human pigmented model(RHPE) Reconstructed human cornel epithelial model(HCE)
*Nikoderm also performs safety and efficacy evaluations using the abovementioned models. |
2003 Establishment of Nikoderm Research Inc.
2004 Installation of evaluation rooms and cell culture rooms in Head Office
2009 Conclusion of agreement with SkinEthic Laboratories,France,as its exclusive agent in Japan
